Application of new coatings for vascular grafts based on polyacrylic systems with antiaggregating activity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 7986939.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A study has been made of the behaviour of knitted and woven Dacron mesh used in the preparation of vascular grafts when coated with either a layer of poly(2-hydroxyethyl methacrylate) or co-polymers of 2-hydroxyethyl methacrylate with 5, 10 or 20 wt% of an acrylic derivative of salicylic acid, 2-methacryloyloxybenzoic acid. In vitro studies were carried out to quantify the loss of polymer under flow conditions, and ex vivo studies were done in dogs to quantify the deposition of 111In-oxine-labelled platelets. The treated materials showed a lesser deposition of platelet thrombi when compared with the control group.
Medical subject headings
- Biocompatible Materials
- Blood Vessel Prosthesis
- Methacrylates
- Polyhydroxyethyl Methacrylate