Myoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine.
case_report · Level V
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- Record sourced from PubMed, PMID 7993994.
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Abstract
Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors is reviewed. The potential mechanisms of myoglobinuria and nephrotoxicity and the therapeutic implications are discussed.
Medical subject headings
- Acute Kidney Injury
- Cyclosporine
- Heart Transplantation
- Lovastatin
- Myoglobinuria
- Rhabdomyolysis