Effects of a long-term transfusion regimen on sickle cell-related illnesses.

Styles, L A; Vichinsky, E · J Pediatr · 1994

prospective_cohort · Level II

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Abstract

The efficacy of a long-term transfusion regimen in preventing sickle cell disease complications is unknown. We examined 17 patients before, during, and after transfusion for cerebral vascular accident and vaso-occlusive crisis. Total hospitalization rate, as well as admissions for vaso-occlusive crisis, cases of acute chest syndrome, and bacterial infections decreased while patients were on a transfusion regimen.

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