Nuclear transcription factors: potential targets for new modes of intervention in skin disease.
review · Level V
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Abstract
Many drugs already in use for the treatment of skin disease, including steroids, retinoids, vitamin D derivatives and cyclosporin (CyA), exert effects on gene transcription. In this review we briefly outline how these drugs work, before proceeding to a consideration of how new drugs acting on the transcription process might be used to influence skin disease.
Medical subject headings
- Skin Diseases
- Transcription Factors
- Transcription, Genetic