Continuous current source inversion of evoked potential fields in a spherical model head.

Abstract

This study explores the efficacy of a physiological constraint on cortical current generators in promoting a robust solution for the inverse problem in evoked potentials. It is proposed that the current sources responsible for the evoked potential be modeled as a set of dipoles oriented orthogonal to the surface of the cortex. Rather than using a minimum norm approach, the solution space is searched for a vector that minimizes the error of the predicted evoked potential scalp field.