Budd-Chiari syndrome associated with antiphospholipid antibodies in a child: report of a case and review of the literature.

Saca, L F; Szer, I S; Henar, E; Nanjundiah, P; Haddad, Z H; Quismorio, F P · J Rheumatol · 1994

case_report · Level V

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Abstract

Budd-Chiari syndrome, hypertension, and thrombocytopenia developed in a 6-year-old girl as manifestations of primary antiphospholipid antibody syndrome (APS). She improved with systemic corticosteroid and anticoagulation therapy. Anticardiolipin antibodies were found in the patient, her mother and 3 siblings, suggesting the importance of genetic factors. The clinical features of an APS in children is reviewed.

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