Sphenoid wing meningioma progression after placement of a subcutaneous progesterone agonist contraceptive implant.
case_report · Level V
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Abstract
A causal relationship between sex steroids and meningioma proliferation has long been suspected. We report a case of the clinical progression of a sphenoid wing meningioma after the placement of Norplant, a subcutaneous contraceptive implant containing levonorgestrel, a progesterone agonist. Although not proof of causation, this observation lends further credence to the importance of progesterone receptors in the growth and possible treatment of meningiomas.
Medical subject headings
- Levonorgestrel
- Meningeal Neoplasms
- Meningioma
- Neoplasms, Hormone-Dependent