Response to suxamethonium during propofol-fentanyl-N2O/O2 anaesthesia in a patient with active myasthenia gravis receiving long-term anticholinesterase therapy.
case_report · Level V
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Abstract
We describe the effect of repeated suxamethonium doses during propofol-fentanyl-N2O/O2 anaesthesia in a 29-year-old woman with active myasthenia gravis receiving chronic pyridostigmine therapy. Despite adequate pre-operative pseudocholinesterase activity, suxamethonium resistance occurred. Neither bradycardia nor residual neuromuscular block were seen after repeated doses of suxamethonium.
Medical subject headings
- Anesthesia, Inhalation
- Anesthesia, Intravenous
- Myasthenia Gravis
- Propofol
- Pyridostigmine Bromide
- Succinylcholine