Magnetic resonance imaging in the evaluation of clinical trials in multiple sclerosis.

Paty, D W; Li, D K; Oger, J J; Kastrukoff, L; Koopmans, R; Tanton, E; Zhao, G J · Ann Neurol · 1994

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Abstract

Magnetic resonance imaging (MRI) provides an objective method of evaluating multiple sclerosis clinical trials and is at least five times more sensitive to disease activity. In a recent clinical trial, MRI was also approximately twice as sensitive as clinical measurements to the treatment effect of a drug.

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