Alpha thalassaemia mental retardation (ATR-X): an atypical family.

Logie, L J; Gibbons, R J; Higgs, D R; Brown, J K; Porteous, M E · Arch Dis Child · 1994

case_report · Level V

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Abstract

A novel form of severe, X linked mental retardation associated with alpha thalassaemia (ATR-X syndrome) has recently been described. Two affected cousins are described, one of whom has an unusually mild haematological phenotype. HbH inclusions, which are the hallmark of this disease, were only detected in the peripheral red blood cells after repeated observations.

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