Cerebellum and brainstem vasculopathy in systemic lupus erythematosus: two clinico-pathological cases.

Smith, R W; Ellison, D W; Jenkins, E A; Gallagher, P J; Cawley, M I · Ann Rheum Dis · 1994

case_report · Level V

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Abstract

The case histories are reported of two patients with systemic lupus erythematosus (SLE) who developed fatal neurological involvement, each presenting with cerebellar and brainstem signs. Neuro-pathological changes were confined to the cerebellum and brainstem, with clear evidence of a small vessel vasculopathy. The predominant histological abnormalities were multiple perivascular haemorrhages in one case and classical vasculitic changes in the other.

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