Evaluation of a DNA probe assay (Gen-Probe PACE 2) as the test of cure for Neisseria gonorrhoeae genital infections.

Hanks, J W; Scott, C T; Butler, C E; Wells, D W · J Pediatr · 1994

case_series · Level IV

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Abstract

A DNA probe (Gen-Probe PACE 2) detects portions of viable and nonviable organisms, and test results could remain positive after effective treatment of genital Neisseria gonorrhoeae infection. Twenty patients underwent test-of-cure studies 6 to 11 days after standard treatment for gonorrhea; in each case the DNA probe finding was negative. The Gen-Probe PACE 2 probe is reliable for test-of-cure study as early as 6 days after treatment.

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