Hepatitis B vaccination in infants of mothers infected with human immunodeficiency virus.

Zuccotti, G V; Riva, E; Flumine, P; Locatelli, V; Fiocchi, A; Tordato, G; Giovannini, M · J Pediatr · 1994

case_series · Level IV

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Abstract

Eighteen infants of mothers with human immunodeficiency virus (HIV) infection were given hepatitis B vaccine at birth. Seroconversion occurred in all 13 infants whose HIV antibody disappeared, versus one of five HIV-infected children. The four of five HIV-infected infants who did not mount an antibody response progressed rapidly to full-blown acquired immunodeficiency syndrome. Thus HIV-infected infants respond poorly to hepatitis B vaccine.

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