Electrocardiographic findings in Rett syndrome: an explanation for sudden death?

Sekul, E A; Moak, J P; Schultz, R J; Glaze, D G; Dunn, J K; Percy, A K · J Pediatr · 1994

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Abstract

Girls with Rett syndrome had significantly longer corrected QT intervals (p < 0.001) and more T-wave abnormalities (p < 0.001) than were found in age-matched healthy girls. With advancing stages of the syndrome, the proportion of corrected QT interval prolongations and T-wave changes increased. The findings suggest a possible cardiac basis for sudden, unexpected death in Rett syndrome.

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