The severity of postischemic hypoperfusion increases with duration of cerebral ischemia in rats.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 8023664.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Regional cerebral blood flow was studied after a period of hypotensive bilateral carotid occlusion in rats. As other studies have found, we confirm that 15 min of ischemia caused an initial brief hyperemic episode followed by severe hypoperfusion in all areas. With varying duration of ischemia from 5 to 10, 15 and 20 min, the median cerebral blood flow 60 min postischemia was 79%, 46%, 48% and 34% of control, respectively. Thus the degree of postischemic hypoperfusion increased significantly with the duration of ischemia.
Medical subject headings
- Cerebrovascular Circulation
- Ischemic Attack, Transient