Islet amyloidosis in a patient with chronic massive insulin resistance due to antiinsulin receptor antibodies.
case_report · Level V
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- Record sourced from PubMed, PMID 8027243.
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Abstract
We report islet hyperplasia, nesidioblastosis, and abundant islet amyloidosis (derived from islet amyloid polypeptide) in a case of severe insulin resistance due to a circulating antiinsulin receptor antibody. Massive chronic beta-cell stimulation (as well as noninsulin-dependent diabetes mellitus and insulinoma) appears to be associated with islet amyloid.
Medical subject headings
- Amyloidosis
- Autoantibodies
- Insulin Resistance
- Islets of Langerhans
- Pancreatic Diseases
- Receptor, Insulin