High-resolution mass spectrometer for protein chemistry.

Li, Y; Hunter, R L; McIver, R T · Nature · 1994

basic_science · Level V

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Abstract

Matrix-assisted laser desorption/ionization is an accurate and sensitive method for measuring the molecular weights of peptides and proteins. Usually time-of-flight mass spectrometry is used to detect the laser-produced ions, but a new method called Fourier transform mass spectrometry offers greater sensitivity and much higher mass measurement accuracy.

Medical subject headings