Once daily antibiotic regimen in paediatric oncology.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 8048816.
- Also identified by PMC identifier 1029865.
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Abstract
The feasibility and efficacy of a once daily antibiotic regimen were assessed in children with malignant tumours. Over a 44 month period, 296 febrile episodes were treated with a regimen of once daily ceftriaxone-amikacin (and teicoplanin or vancomycin if the patient had a central line). The treatment was successful in 272 (92%) episodes without modification of the antibiotic regimen, and only one patient died of uncontrolled sepsis. A once daily antibiotic regimen is therefore feasible and worthwhile in the treatment of febrile episodes in children with cancer.
Medical subject headings
- Bacterial Infections
- Drug Therapy, Combination
- Neoplasms