Liposomal amphotericin B in hepatic candidosis.

Sharland, M; Hay, R J; Davies, E G · Arch Dis Child · 1994

case_report · Level V

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Abstract

A 4 year old girl treated with a standard chemotherapy protocol for acute lymphoblastic leukaemia developed hepatic candidosis during the consolidation phase. This relapsed after a prolonged course of amphotericin B and flucytosine. An eight week course of liposomal amphotericin produced a marked clinical improvement which was sustained for one year. A subsequent relapse was associated with transformation to myelodysplastic leukaemia.

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