Radiotracer measurement of ureteric blood flow.

Mooney, E F; Geraghty, J G; O'Connell, M; Kent, P; Angerson, W; Quereshi, A; Sarazen, A; Fitzpatrick, J M · J Urol · 1994

basic_science · Level V

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Abstract

This paper describes a novel technique using the blood flow tracer C14-iodoantipyrine to measure ureteric blood flow in anesthetized Sprague-Dawley rats. The ureters were divided into five equal segments, and the blood flow was measured using a modification of the Fick principle. There was a gradient down the ureter with a significant difference between upper (159 ml./100 gm./min.) and lower (83 ml./100 gm./min.) ureteric segmental blood flows. This technique may allow the role of ureteric ischemia to be investigated in a variety of disease states.

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