Intestinal permeability in patients with Crohn's disease and their first-degree relatives.
cross_sectional · Level IV
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Abstract
To measure small intestinal permeability in a group of patients with Crohn's disease in clinical remission and their apparently healthy first-degree relatives. Administration of 51Cr-labeled EDTA and subsequent measurement of its excretion in a 24-h urine collection. Excretion of 51Cr-EDTA was not elevated in either the patients or in first-degree relatives. Intestinal permeability to 51Cr-EDTA is not raised in patients with Crohn's disease in clinical remission or in their healthy first-degree relatives.
Medical subject headings
- Crohn Disease
- Intestinal Absorption
- Intestine, Small