Fatal group A streptococcal meningitis and toxic shock-like syndrome: case report.

Jevon, G P; Dunne, W M; Hawkins, H K; Armstrong, D L; Musser, J M · Clin Infect Dis · 1994

case_report · Level V

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Abstract

A previously healthy 8-year-old girl presented with flu-like symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A beta-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA 2) that has recently been associated with widespread toxic shock-like syndrome.

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