Accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate therapy.

Abu-Shakra, M; Nicol, P; Urowitz, M B · J Rheumatol · 1994

case_report · Level V

Where this comes from

Abstract

We describe a patient with seropositive erosive rheumatoid arthritis (RA) who developed accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate (MTX) therapy while her arthritis remained inactive. MTX is an effective therapy for the articular manifestations of RA. However, on occasion it may result in triggering the development of extraarticular manifestations of RA.

Medical subject headings