Controlling chaos in the brain.

Schiff, S J; Jerger, K; Duong, D H; Chang, T; Spano, M L; Ditto, W L · Nature · 1994

basic_science · Level V

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Abstract

In a spontaneously bursting neuronal network in vitro, chaos can be demonstrated by the presence of unstable fixed-point behaviour. Chaos control techniques can increase the periodicity of such neuronal population bursting behaviour. Periodic pacing is also effective in entraining such systems, although in a qualitatively different fashion. Using a strategy of anticontrol such systems can be made less periodic. These techniques may be applicable to in vivo epileptic foci.

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