Maternal mild hyperphenylalaninemia: results of treated and untreated pregnancies in two sisters.
case_control · Level III
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- Record sourced from PubMed, PMID 8071761.
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Abstract
The outcomes of mild hyperphenylalaninemia (MHP) in three children of two sisters were compared. The IQ of the child from an untreated pregnancy was 105; the developmental quotients of the two infant offspring from treated and untreated pregnancies were 122 and 114, respectively. The IQ of the sister with untreated MHP was 101; that of the sister who received dietary treatment for MHP during infancy was 90. Thus MHP and maternal MHP appear to have been clinically inconsequential in this family.
Medical subject headings
- Intelligence
- Phenylalanine
- Pregnancy Complications