Memory of DL-polylactic acid biodegradable plates.

Losken, H W; Tschakaloff, A; von Oepen, R; Mooney, M P; Moritz, O; Michaeli, W; Lalikos, J; Losken, A · Ann Plast Surg · 1994

basic_science · Level V

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Abstract

Biodegradable plates and screws have many advantages over metal plates and screws. Plates were injection-molded and made of DL-polylactic acid. Four-hole plates were bent with the use of a heated tip to angles of 30, 45, and 60 degrees. They were inserted in the subcutaneous space in the back of rabbits. After 2 weeks, the plates straightened, suggesting that the plates had a memory. The results were confirmed by similar in vitro investigations. The in vitro experiment was repeated with tempering of the plates. The plates were heated to a temperature of 200 degrees C for 45 seconds, cooled, and then again heated to 200 degrees C for 40 seconds. This process resulted in loss of memory of the plates. After 4 weeks, there was a change of the bending angle of less than 2.5 degrees.

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