The ancient regulatory-protein family of WD-repeat proteins.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 8090199.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
WD proteins are made up of highly conserved repeating units usually ending with Trp-Asp (WD). They are found in all eukaryotes but not in prokaryotes. They regulate cellular functions, such as cell division, cell-fate determination, gene transcription, transmembrane signalling, mRNA modification and vesicle fusion. Here we define the common features of the repeating units, and criteria for grouping such proteins into functional subfamilies.
Medical subject headings
- Proteins
- Repetitive Sequences, Nucleic Acid