The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head.
basic_science · Level V
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- Record sourced from PubMed, PMID 8099441.
- Also identified by PMC identifier 46537.
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Abstract
Avian sarcoma virus 31 contains an oncogene that we have named qin. qin codes for a nuclear protein, Qin, that is a member of the HNF-3/fork head family of transcriptional regulators. Within this family Qin is particularly closely related to rat brain factor 1 (BF-1), a telencephalon-specific gene presumed to play an important role in the development of the mammalian brain.
Medical subject headings
- Avian Sarcoma Viruses
- Genes, Homeobox
- Nuclear Proteins
- Oncogenes
- Transcription Factors