Vitamin E treatment of tardive dyskinesia.

Adler, L A; Peselow, E; Rotrosen, J; Duncan, E; Lee, M; Rosenthal, M; Angrist, B · Am J Psychiatry · 1993

rct · Level II

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Abstract

The authors studied the effects of vitamin E treatment of tardive dyskinesia; earlier studies have produced contradictory results. Twenty-eight patients with tardive dyskinesia were treated in a double-blind, parallel-group comparison study of 8-12 weeks of treatment with vitamin E (1600 IU/day) or matching placebo capsules. The Abnormal Involuntary Movement Scale scores of the patients treated with vitamin E improved significantly compared to the scores of the patients given placebo. These results support earlier findings of the efficacy of vitamin E in treating tardive dyskinesia.

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