Correction of Duncan's syndrome by allogeneic bone marrow transplantation.

Williams, L L; Rooney, C M; Conley, M E; Brenner, M K; Krance, R A; Heslop, H E · Lancet · 1993

case_report · Level V

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Abstract

Duncan's syndrome (X-linked lymphoproliferative disorder) is a fatal immunodeficiency syndrome of unknown aetiology and without cure. We show that allogeneic bone marrow transplantation can correct the lethal immune deficits in a patient with this syndrome. We suggest that the primary abnormality in Duncan's syndrome is in bone-marrow derived cells.

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