Oligonucleotide probe design--a new approach.

Mitsuhashi, M; Cooper, A; Ogura, M; Shinagawa, T; Yano, K; Hosokawa, T · Nature · 1994

basic_science · Level V

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Abstract

The use of oligonucleotides for gene amplification, as diagnostic probes or antisense-based drugs can be optimized by minimizing the possibility of nonspecific hybridization.

Medical subject headings