Cancer-associated retinopathy with retinal phlebitis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 8110675.
- Also identified by PMC identifier 504659.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A 50-year-old man with cancer-associated retinopathy was investigated using light and electron microscopy, immunofluorescence studies, and western blotting. He had visual disturbance, ring-like scotoma, and night blindness bilaterally. There were narrowed retinal arterioles and dilated retinal venules. Oral corticosteroid therapy had positive effects. Immunostaining using the patient's serum revealed a positive reaction in the ganglion cell layer of normal retina. Western blotting showed that the patient's serum antibody reacted with normal retinal proteins of 24 and 48 kDa. Multiple metastases were evident at autopsy.
Medical subject headings
- Carcinoma, Small Cell
- Lung Neoplasms
- Phlebitis
- Retinal Diseases