Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene.
basic_science · Level V
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Abstract
The rum1+ gene is identified as a new regulator of G1 progression in fission yeast. It influences three aspects of G1 regulation: determination of the length of G1, dependence of S phase upon completion of mitosis, and restraint of mitosis until G1 is finished. We propose that it has a central role in regulating the G1 phase of the cell cycle.
Medical subject headings
- Cell Cycle
- Fungal Proteins
- Genes, Fungal
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins