Intravascular malignant lymphomatosis: amelioration of neurological symptoms with plasmapheresis.

Harris, C P; Sigman, J D; Jaeckle, K A · Ann Neurol · 1994

case_report · Level V

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Abstract

Intravascular malignant lymphomatosis is a rare disease that is uniformly fatal when disseminated. Chemotherapeutic and radiation therapy regimens have provided short-term amelioration of symptoms but have not affected overall survival. We describe a patient with diffuse neurological symptoms who responded transiently but dramatically to plasmapheresis. This marked response warrants further evaluation of this therapy in intravascular malignant lymphomatosis.

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