A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast.
basic_science · Level V
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- Record sourced from PubMed, PMID 8127913.
- Also identified by PMC identifier 43282.
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Abstract
A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.
Medical subject headings
- DNA Helicases
- Fungal Proteins
- Nuclear Proteins
- Saccharomyces cerevisiae