Pulmonary sequestration with primary blastomycosis. Failure of ketoconazole therapy after resection.
case_report · Level V
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Abstract
Infection with Blastomyces dermatitidis developed in a girl with occult pulmonary sequestration. Six months after resection, while receiving ketoconazole, she developed an abscess due to B dermatitidis over the scar from thoracotomy, with a sinus tract to the eighth rib. This was successfully managed with débridement, rib resection, and amphotericin B. Contiguous bone involvement should be suspected in sequestra infected with this organism; débridement and therapy with amphotericin B might be indicated.
Medical subject headings
- Blastomycosis
- Bronchopulmonary Sequestration
- Ketoconazole
- Lung Diseases, Fungal