Misleading hepatitis C serology following administration of intravenous immunoglobulin.

Nixon, R R; Smith, S A; Johnson, R L; Pillers, D A · Am J Clin Pathol · 1994

case_report · Level V

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Abstract

Intravenous immunoglobulin (IVIG) is a blood derivative that is being evaluated for the prevention and treatment of numerous disorders. Recent studies have suggested beneficial effects from the prophylactic administration of IVIG to very-low-birth-weight neonates. A disadvantage of such therapy is misleading infectious disease serologic assays following administration of IVIG. The authors report a recent case in their neonatal intensive care unit of a 24-week gestational age girl with a misleading positive hepatitis C serology reaction following IVIG administration.

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