Multi-target PCR analysis by capillary electrophoresis and laser-induced fluorescence.

Lu, W; Han, D S; Yuan, J; Andrieu, J M · Nature · 1994

basic_science · Level V

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Abstract

Quantitative analysis of polymerase chain reaction (PCR) amplified HIV-1 DNA or cDNA fragments is attained using an automated system that combines capillary-gel electrophoresis (CGE) for high-efficiency separation and laser-induced fluorescence (LIF) for high-sensitivity detection. This system enables the detection of PCR-amplified multiple target DNA or cDNA in the same tube by a single injection with high precision.

Medical subject headings