Electron-beam therapy in scleredema adultorum with associated monoclonal hypergammaglobulinaemia.

Angeli-Besson, C; Koeppel, M C; Jacquet, P; Andrac, L; Sayag, J · Br J Dermatol · 1994

case_report · Level V

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Abstract

We report a case of scleredema adultorum (Buschke's disease) associated with an IgA kappa monoclonal hypergammaglobulinaemia. A significant improvement in the skin was obtained with electron-beam therapy. Scleredema would appear to be linked to monoclonal hypergammaglobulinaemia, but the relationship between the skin disorder and the immunoglobulin abnormality remains to be elucidated.

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