Osseous substance formation induced in porous calcium phosphate ceramics in soft tissues.
basic_science · Level V
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Abstract
Porous calcium phosphate ceramics prepared according to the methods of laboratories in Leiden were implanted subcutaneously in rats for 3, 6 and 12 w. No bone formation could be observed. Porous calcium phosphate ceramics prepared according to the methods of laboratories in Sichuan were implanted subcutaneously/intramuscularly in dogs for 1, 3, 5 and 7 months. In particular, ceramics containing alpha-tricalcium phosphate evoked bone formation in the pores of the ceramics. The amount of bone was similar at the different time periods.
Medical subject headings
- Bone Development
- Calcium Phosphates
- Ceramics
- Prostheses and Implants