Werner's syndrome associated with spastic paraparesis and peripheral neuropathy.
case_report · Level V
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Abstract
A Werner's syndrome patient with spastic paraparesis and polyneuropathy had slowing of central and peripheral nerve conduction. Sural nerve biopsy revealed a significantly higher frequency of demyelination and remyelination and a loss of myelinated fibers. These data suggest that the central and peripheral nervous systems are affected in Werner's syndrome.
Medical subject headings
- Demyelinating Diseases
- Paraparesis, Tropical Spastic
- Peripheral Nervous System Diseases
- Werner Syndrome