Acute hypoxemic respiratory failure following intrapleural thrombolytic therapy for hemothorax.

Frye, M D; Jarratt, M; Sahn, S A · Chest · 1994

case_report · Level V

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Abstract

Intrapleural instillation of thrombolytic agents has been useful in the treatment of hemothorax when thoracostomy tube drainage is unsuccessful. We present a patient who developed acute hypoxemic respiratory failure following the intrapleural instillation of both streptokinase and urokinase 24 h apart. Hypoxemia most likely resulted from a direct effect of the products of fibrinolysis on the pulmonary circulation.

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