Severe diffuse interstitial pneumonitis induced by carmustine (BCNU).

Lena, H; Desrues, B; Le Coz, A; Quinquenel, M L; Delaval, P · Chest · 1994

case_report · Level V

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Abstract

We report a fatal case of acute interstitial pneumonitis in a patient treated with carmustine (BCNU) for a brain tumor. Bronchoalveolar lavage (BAL) revealed lymphocyte alveolitis with a low CD4/CD8 ratio (0.36), consistent with an immunoallergic phenomenon, rather than the most often evoked toxic hypothesis.

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