Paternal pericentric inversion of chromosome 4 as a cause of recurrent pregnancy loss.

Wolf, G C; Mao, J; Izquierdo, L; Joffe, G · J Med Genet · 1994

case_report · Level V

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Abstract

A paternal pericentric inversion of chromosome 4 was ascertained through karyotype analysis of an abortus specimen proven to be 46,XX,rec(4),dup q, inv (4)(p13q28). The relationship of paternal pericentric inversion to pregnancy loss is discussed, and a recommendation for karyotype analysis of recurrent abortion specimens is made.

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