Pain modulation and the action of analgesic medications.

Fields, H · Ann Neurol · 1994

review · Level V

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Abstract

A general approach to improving the treatment of patients with post-herpetic neuralgia is outlined. Pain-generating processes initiated by injury to peripheral nerve and new treatments that target these processes are discussed. Another described approach is to use knowledge of central nervous system pain-modulating networks to improve the effectiveness of centrally acting analgesics such as opioids and tricyclic antidepressants.

Medical subject headings