Relevance of broad-spectrum and fungicidal activity of antifungals in the treatment of dermatomycoses.
other · Level V
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Abstract
The in vitro fungistatic and fungicidal activities of terbinafine, amorolfine and itraconazole against dermatophytes were compared. All three compounds showed very good activity against all dermatophyte species tested, but only terbinafine and amorolfine exhibited primary fungicidal activity. These two compounds were also active in vitro against other filamentous fungi which cause onychomycoses, such as Scytalidium and Scopulariopsis species.
Medical subject headings
- Antifungal Agents
- Arthrodermataceae
- Mitosporic Fungi