Amnesic syndrome after theophylline associated seizures: iatrogenic brain injury.
case_report · Level V
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- Record sourced from PubMed, PMID 8201347.
- Also identified by PMC identifier 1072938.
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Abstract
Two patients developed a disabling amnesic syndrome after seizures associated with oral theophylline treatment. Such seizures are more likely in the elderly, in the presence of pre-existing neurological disease, and when theophylline is given with certain antibiotics and cimetidine. The mechanism of neuronal injury may be by the excessive release of endogenous excitotoxic glutamate.
Medical subject headings
- Amnesia
- Seizures
- Theophylline