A fatal case of scleredema of Buschke.

Sansom, J E; Sheehan, A L; Kennedy, C T; Delaney, T J · Br J Dermatol · 1994

case_report · Level V

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Abstract

Scleredema of Buschke is a rare disorder characterized by the development of areas of skin induration which usually resolve spontaneously. It is occasionally associated with a benign gammopathy, and rarely with myelomatosis. We describe a 60-year-old woman with extensive skin changes, who developed IgA myeloma. Unusually, her skin disease did not respond to conventional myeloma therapy. Death occurred as a consequence of the progressive skin disease.

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