A genetic linkage map of the mouse: current applications and future prospects.

Copeland, N G; Jenkins, N A; Gilbert, D J; Eppig, J T; Maltais, L J; Miller, J C; Dietrich, W F; Weaver, A et al. · Science · 1993

review · Level V

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Abstract

Technological advances have made possible the development of high-resolution genetic linkage maps for the mouse. These maps in turn offer exciting prospects for understanding mammalian genome evolution through comparative mapping, for developing mouse models of human disease, and for identifying the function of all genes in the organism.

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