Nonlinear summation of junction potentials in a three-dimensional syncytium.
basic_science · Level V
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Abstract
A three-dimensional "cable" equation with reversal potentials is derived for an infinite syncytium. Its solution is found analytically by using Green's function methods for the special case of two impulsive conductance changes activated at different "points" in space. It is shown that junction potentials generated at different sites in the syncytium do not in theory sum linearly.
Medical subject headings
- Action Potentials
- Intercellular Junctions
- Intracellular Membranes
- Models, Neurological
- Muscle, Smooth, Vascular
- Synapses
- Varicose Veins